Around 50 percent of people harbour yeast fungi in their bodies. In general, our immune systems manage to keep these troublesome tenants under control. However, yeast fungi do cause several thousand deaths each year in Germany alone – and the figures are rising. People with weakened immune systems, such as chemotherapy patients and transplant recipients, are particularly susceptible to potentially fatal mycoses, which are aggressive fungal infections. At present, only a few drugs are available for the treatment of such diseases and some of them can cause considerable side-effects. To make matters worse, the fungi are becoming increasingly resistant to the drugs used to combat them. Now, researchers from Fraunhofer IGB and experts from EMC microcollections GmbH are collaborating on a research project aimed at identifying new compounds which have a broad spectrum of effect against a variety of different fungi and are more easily tolerated than conventional antimycotics.