Fraunhofer Institute for Interfacial Engineering and Biotechnology IGBWe produce materials that can be used to coat surfaces, but also in 3D printing processes. Depending on the application, the materials are synthesized, chemically modified or suitably formulated. The materials are hydrogels, drug-releasing particles, and formulations for coatings and bioprinting.
Different functional materials.
© Fraunhofer IGB
Materials
Tabbed contents
Range of services
NANOCYTES®/core-shell particles
- Development and synthesis of highly specific adsorber polymers
- Development of NANOCYTES® surfaces for DNA- and protein microarrays
- Surface coating of micro- and nanoparticles
- Design and production of selective composite membranes
- Organic and inorganic particle-based systems
- Formulation of drug matrix systems
- Development of biocompatible and biodegradable particles
- Loading and encapsulating of particles
- Production of nanoparticles with reactive active ester surface
- Bioconjugation of biomolecules on surfaces
- Biological analyses and analytics
- Carrying out feasibility studies
Development of nano- and micro-encapsulated active agents
- Synthesis of polymers and block co-polymers
- Characterization of polymers
- Bioconjugation
Drug loading of particles
- Formulation of particles via mini- and nano-spray dryer
- High performance liquid chromatography (HPLC)
- Titration microcalorimetry
Printing processes
- Formulation of water- or solvent-based inkjet inks
- Biofunctional inks
- Inks containing nano- or microparticles
- UV-crosslinkable inks
- Conductive and printed circuit board inks
- Printing of high-resolution structures
Equipment
Analytics
Biological and polymer analysis
- MALDI-TOF/TOF mass spectrometer (Bruker Ultraflex II)
- Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)
- Simultaneous thermoanalysis (STA)
- Gel permeation chromatography (GPC) with 4 detectors
Particle analysis
- Microelectrophoresis (zeta potential)
- Dynamic light scattering (SLS, mastersizer, measuring range 0.1 nm to 10 μm)
- Static light scattering (SLS, mastersizer, measuring range 50 nm to 2 mm)
- Miniplants with inline analytics
Surface characteristics and morphology
- Ellipsometry
- Microscopy, scanning electron microscope (REM), atomic force microscopy (AFM)
- Electron spectroscopy for chemical analysis (ESCA)
- Mini- and nano-spray dryer for the formulation of particles
- High performance liquid chromatography (HPLC)
- Titration microcalorimetry
Formulations
- Dynamic light scattering
- Ellipsometry
- MALDI TOF mass spectrometry
- Microcalorimetry
- Digital imaging
- Laboratory synthesis
Publications and brochures
Scientific publications
| Jahr Year | Titel/Autor:in Title/Author | Publikationstyp Publication Type |
|---|---|---|
| 2010 | Electro photography ("Laser Printing") an efficient technology for biofabrication Güttler, Stefan; Refle, Oliver; Fulga, Simina; Grzesiak, Andrzej; Seifarth, Christian; Stadler, Volker; Weber, Achim; Speyerer, Christian |
Konferenzbeitrag Conference Paper |
| 2010 | Nanopartikel-Enzym-Konjugate für die Entwicklung von Biosensoren Pufky-Heinrich, D.; Weber, A. |
Zeitschriftenaufsatz Journal Article |
| 2010 | Parylenbeschichtung polymerer Werkstoffe Barz, J.; Müller, Michaela; Elkin, B.; Oehr, Christian |
Aufsatz in Buch Book Article |
| 2010 | Dry native protein assays on 3D and 2D substrates by non-contact Laser-Induced-Forward Transfer LIFT process Genov, S.; Thurow, I.; Riester, D.; Hirth, Thomas; Borchers, K.; Weber, A.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2010 | Ink-jet printing of proteins and functional nanoparticles for automated biofunctionalization of surfaces Plankalayil, Jolafin; Weber, A.; Borchers, K. |
Poster |
| 2010 | Ink formulation for the inkjet printing of functional core-shell nanoparticles for automated preparation of multi feature biofunctional surfaces Weber, A.; Borchers, K.; Plankalayil, Jolafin; Hirth, Thomas; Tovar, G. |
Vortrag Presentation |
| 2010 | Dry native protein assays on nitrocellulose coated glass substrates by non-contact laser-induced-forward transfer process Genov, S.; Thurow, I.; Riester, D.; Borchers, K.; Tovar, G.; Hirth, Thomas; Weber, A. |
Poster |
| 2010 | Nanopartikel für jetbasierte Beschichtungsanwendungen im Bereich der Lebenswissenschaften Weber, A. |
Vortrag Presentation |
| 2010 | Verfahren zur chemischen Tonerfixierung Hirth, T.; Weber, Achim; Speyerer, C.; Borchers, Kirsten; Tovar, G. |
Patent |
| 2010 | Particle dynamics simulation and diagnostics of the PECVD processes in fluorocarbon rf discharges Barz, J.P. |
Dissertation Doctoral Thesis |
| 2010 | Geprägte Polymernanopartikel zur molekularen Wiedererkennung von Wirkstoffen Schreiber, T.; Riegler, J.; Gruber-Traub, C.; Hirth, Thomas; Tovar, G. |
Poster |
| 2010 | NANOCYTES-Technology - Biomimetic nanoparticles for molecular recognition by molecular imprinting Schreiber, T.; Niedergall, Klaus; Wojciukiewicz, D.; Gose, Thomas; Gruber-Traub, Carmen; Weber, Achim; Hirth, Thomas; Tovar, Günter |
Konferenzbeitrag Conference Paper |
| 2010 | Dry native proteins printed on 3D and 2D substrates by non-contact Laser-Induced-Forward Transfer (LIFT) Genov, S.; Riester, D.; Borchers, K.; Tovar, G.; Hirth, Thomas; Weber, A. |
Poster |
| 2009 | Vorrichtung und Verfahren zur Oberflaechenbehandlung partikulaerer und pulverfoermiger Substrate im Fliessbett Zschörper, N.P.; Barz, J.; Vohrer, U.; Oehr, C. |
Patent |
| 2009 | Chemical and gas-phase kinetics in a CHF3 + Ar discharge Barz, Jakob Philipp; Lunk, A.; Oehr, Christian |
Konferenzbeitrag Conference Paper |
| 2009 | In vitro study of mouse fibroblast tumor cells with TNF coated and Alexa488 marked silica nanoparticles with an endoscopic device for real time cancer visualization Herz, Marion; Rank, Andreas; Tovar, Günter E.M.; Hirth, Thomas; Kaltenbacher, Dominik; Stallkamp, Jan; Weber, Achim |
Konferenzbeitrag Conference Paper |
| 2009 | Biomimetic nanoparticles providing molecularly defined binding sites - protein-featuring structures versus molecularly imprinted polymers Borchers, K.; Genov, S.; Gruber-Traub, C.; Niedergall, K.; Plankalayil, J.; Pufky-Heinrich, D.; Riegler, J.; Schreiber, T.; Tovar, G.E.M.; Weber, A.; Wojciukiewicz, D. |
Aufsatz in Buch Book Article |
| 2009 | Water treatment by molecularly imprinted polymer nanoparticles Schreiber, T.; Weber, Achim; Niedergall, Klaus; Hirth, Thomas; Tovar, Günter; Riegler, Jürgen; Bryniok, Dieter |
Konferenzbeitrag Conference Paper |
| 2009 | Ink-jet printing of proteins and functional nanoparticles for automated functionalization of surfaces Knaupp, Markus; Grzesiak, Andrzej; Weber, Achim; Hirth, Thomas; Tovar, Günter E.M.; Borchers, Kirsten |
Konferenzbeitrag Conference Paper |
| 2009 | C-VIS: Interoperative Tumorerkennung mit Hilfe von Nanopartikeln Weber, Achim; Herz, Marion; Hirth, Thomas; Tovar, Günter E.M.; Stallkamp, Jan; Kaltenbacher, Dominik |
Zeitschriftenaufsatz Journal Article |
| 2008 | Molekular geprägte Polymere Borchers, K.; Gruber-Traub, C.; Dettling, M.; Heubach, D.; Hirth, Thomas; Tovar, G.E.M. |
Aufsatz in Buch Book Article |
| 2008 | Untersuchungen der Miniemulsionspolymerisation von EGDA-co-MAA und Ermittlung der Prozessparameter Pfeiffer, D.; Weber, A.; Hirth, Thomas; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2008 | Untersuchung der Miniemulsionspolymerisation von EGDMA-co-MAA und Ermittlung der Prozessparameter Pfeiffer, Daniel; Weber, Achim; Hirth, Thomas; Tovar, Günter |
Konferenzbeitrag Conference Paper |
| 2008 | Verbesserte dreidimensionale biokompatible Gerüststruktur, die Nanopartikel beinhaltet Brunner, H.; Mertsching, H.; Schweizer, P.; Weimer, M.; Weber, Achim; Tovar, G.; Borchers, Kirsten |
Patent |
| 2008 | Highly integrated polymer-based technology platform for in-vitro diagnostics Otto, Thomas; Nestler, Jörg; Morschhauser, Andreas; Schüller, Martin; Geßner, T.; Krissler, Jan; Ebling, Frank; Wegener, Michael; Grzesiak, Andrzej; Burgard, Matthias; Brandenburg, Albrecht; Sulz, Gerd; Nebling, Eric; Hintsche, Rainer; Wirth, Ingo; Godlinski, Dirk; Tovar, Günter E.M.; Weber, Achim; Ehrentreich-Förster, Eva; Gajovic-Eichelmann, Nenad; Bier, Frank F. |
Konferenzbeitrag Conference Paper |
| 2008 | Parylenbeschichtung polymerer Werkstoffe Barz, J.; Elkin, B.; Müller, Michael; Oehr, Christian |
Aufsatz in Buch Book Article |
| 2008 | Biofunctional core-shell nanoparticle deposition for biochip creation by printing processes Plankalayil, Jolafin; Genov, Sandra; Borchers, Kirsten; Grzesiak, Andrzej; Hirth, Thomas; Weber, Achim; Tovar, Günter E.M. |
Konferenzbeitrag Conference Paper |
| 2008 | Creation and recombination of free radicals in fluorocarbon plasma polymers Haupt, Michael; Barz, J.; Oehr, Christian |
Zeitschriftenaufsatz Journal Article |
| 2007 | Verfahren zur Gewinnung von Fettbegleitstoffen aus Kraftstoffen und Verwendung dieses Verfahrens Heil, V.; Greve, A.; Weber, Achim; Tovar, G.; Herold, M. |
Patent |
| 2007 | Verbesserte Mikrogele und Filme Tovar, G.; Vaihinger, D.; Kraeuter, I.; Weber, Achim; Brunner, H. |
Patent |
| 2007 | Innovative microchip surfaces for fluorescence spectroscopy and affinity-MALDI mass spectrometry in proteomics Schmucker, J.; Borchers, K.; Weber, A.; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2007 | Functional core-shell nanoparticles for biochemical sensors Weber, A.; Borchers, K.; Brunner, H.; Tovar, G. |
Konferenzbeitrag Conference Paper |
| 2007 | Analytical assessment and functionalization of carbon nanotubes and bucky papers Vohrer, Uwe; Zschörper, N.P.; Katzenmaier, V.; Barz, J.; Oehr, C. |
Konferenzbeitrag Conference Paper |
| 2007 | Verfahren zum Herstellen funktioneller Oberflaechenbereiche auf einem Flaechensubstrat Weber, Achim; Tovar, G.; Borchers, Kirsten; Güttler, S.; Grzesiak, A. |
Patent |
| 2006 | Biomimetic nanoparticles - concept, design and applications in biotechnology and biomedicine Weber, A.; Gruber-Traub, C.; Herold, M.; Borchers, K.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2006 | Fluorocarbon nano coatings for specific surface functionalization Haupt, Michael; Barz, J.; Vohrer, Uwe; Hilgers, H.; Oehr, Christian |
Zeitschriftenaufsatz Journal Article |
| 2006 | POLY 483-Kinetic and thermodynamic behavior of recognition processes employing nano-spherical L-boc-phenylalanine anilide molecularly imprinted poly(MAA-co-EGDMA) monoliths Sezgin, S.; Weber, A.; Herold, M.; Gruber-Traub, C.; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2006 | Nanoparticle-based diagnostic 3D-protein-biochip for Candida albicans Borchers, K.; Hiller, E.; Urban, Constantin; Weber, A.; Rupp, S.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2006 | POLY 474-A detailed investigation of the co-polymerization kinetics and particle formation of nanoscopical poly(EGDMA-co-MAA) by miniemulsion polymerization Herold, M.; Muller, E.; Dettling, M.; Weber, A.; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2006 | NANOCYTES®-based protein-biochip. Mass-sensing device for diagnostic purposes Borchers, K.; Hiller, E.; Weber, A.; Rupp, S.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2006 | Niederdruckplasmaprozesse zur gezielten Funktionalisierung von Grenz- und Oberflächen Haupt, Michael; Barz, J.; Vohrer, Uwe; Oehr, Christian |
Aufsatz in Buch Book Article |
| 2006 | POLY 677-NANOCYTES (TM): Inverse miniemulsion polymerization technology for specific protein recognition Gruber-Traub, C.; Weber, A.; Dettling, M.; Herz, Marion; Herold, M.; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2006 | Dreidimensionale nano- und mikrostrukturierte Traeger Tovar, G.; Weber, Achim; Brunner, H.; Borchers, Kirsten |
Patent |
| 2006 | Influence of fluorocarbon plasma polymer films on the growth of primary human fibroblasts Barz, J.; Haupt, Michael; Pusch, K.; Weimer, M.; Oehr, Christian |
Zeitschriftenaufsatz Journal Article |
| 2005 | ToF-SIMS characterisation of ultra-thin fluorinated carbon plasma polymer films Gradowski, M. von; Jacoby, B.; Hilgers, H.; Barz, J.; Wahl, M.; Kopnarski, M. |
Konferenzbeitrag Conference Paper |
| 2005 | Functional core-shell nanoparticles and applications in protein-bio-chip technology Weber, A.; Borchers, K.; Tovar, G.E.M.; Brunner, H. |
Konferenzbeitrag Conference Paper |
| 2005 | Protein-microarray constituted from streptavidin-coated nanoparticles deposited via poly(electrolyte) multilayers for analysis of biotinylated ligands by MALDI mass spectrometry and fluorescence imaging Weber, A.; Borchers, K.; Schmucker, J.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2005 | Ultrathin carbon-fluorine films Barz, J.; Haupt, Michael; Hilgers, H.; Oehr, C. |
Konferenzbeitrag Conference Paper |
| 2005 | Moorganically modified core-shell nanoparticles for cell signalling Weber, A.; Scheurich, P.; Pflzenmaier, K.; Schiestel, Thomas; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2005 | Nanotechnologische Werkzeuge für die Biotechnologie Gruber-Traub, C.; Lehmann, M.; Tovar, G.E.M.; Brunner, H. |
Zeitschriftenaufsatz Journal Article |
| 2005 | Ultrathin carbon-fluorine film processing Barz, J.; Haupt, Michael; Vohrer, Uwe; Hilgers, H.; Oehr, C. |
Konferenzbeitrag Conference Paper |
| 2005 | Molecular recognition by imprinted polymer nanospheres: Fundamental research and applications Herold, M.; Tovar, G.E.M.; Gruber, C.; Dettling, M.; Sezgin, S.; Brunner, H. |
Konferenzbeitrag Conference Paper |
| 2005 | Fluor-Kohlenstoff-Nanoschichten zur gezielten Oberflächenfunktionalisierung Haupt, Michael; Barz, J.; Vohrer, Uwe; Hilgers, H.; Oehr, Christian |
Zeitschriftenaufsatz Journal Article |
| 2005 | Microstructured layers of spherical biofunctional core-shell nanoparticles provide enlarged reactive surfaces for protein microarrays Borchers, K.; Weber, A.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2005 | Adhesion between fillers and matrices in composite materials Mikonsaari, Irma; Hübner, Christof; Walitza, Eckehard; Gerber, Peter; Chaumette, Christiane; Müller, Michaela |
Konferenzbeitrag Conference Paper |
| 2004 | Modular structure of biochips based on microstructured deposition of functional nanoparticles Weber, A.; Knecht, S.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2004 | Bioconjugative polymer nanospheres studied by isothermal titration calorimetry Weber, A.; Herold, M.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2004 | Bio-microarrays based on functional nanoparticles Tovar, G.E.M.; Weber, A. |
Aufsatz in Buch Book Article |
| 2003 | Investigation of the crystallisation behaviour of lead titanate (PT), lead zirconate (PZ) and lead zirconate titanate (PZT) by EXAFS-spectroscopy and x-ray diffraction Feth, M.P.; Weber, A.; Merkle, R.; Reinöhl, U.; Bertagnolli, H. |
Zeitschriftenaufsatz Journal Article |
| 2003 | Modularer Aufbau von Biochips durch mikrostrukturierte Abscheidung von funktionellen Nanopartikeln Weber, A.; Knecht, S.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2003 | Nanopartikel-Biochips zur Untersuchung von C. albicans Hauser, N.C.; Weber, A.; Tovar, G.; Rupp, S. |
Zeitschriftenaufsatz Journal Article |
| 2003 | Oxygen diffusion in alkyl-substituted titaniumoxo phthalocyanine films Lüer, L.; Egelhaaf, H.-J.; Oelkrug, D.; Winter, G.; Hanack, M.; Weber, A.; Bertagnolli, H. |
Konferenzbeitrag Conference Paper |
| 2003 | Verbesserte strukturiert-funktionale Bindematrices fuer Biomolekuele Weber, Achim; Schiestel, Thomas; Tovar, G.; Brunner, H. |
Patent |
| 2002 | Molecularly imprinted nanospheres as synthetic affinity material for biotechnical application Tovar, G.E.M.; Kräuter, I.; Weber, A.; Dettling, M.; Brunner, H. |
Konferenzbeitrag Conference Paper |
| 2002 | Isothermal titration calorimetry of molecularly imprinted polymer nanospheres Weber, A.; Dettling, M.; Brunner, H.; Tovar, G.E.M. |
Zeitschriftenaufsatz Journal Article |
| 2002 | EXAFS and X-ray diffraction studies on sol-gel prepared zirconium titanium oxides Feth, M.P.; Weber, A.; Merkle, R.; Reinohl, U.; Bertagnolli, H. |
Zeitschriftenaufsatz Journal Article |
| 2002 | Bioactive microarrays by microstructured deposition of functional nanoparticles Tovar, G.E.M.; Weber, A.; Schiestel, Thomas; Knecht, S.; Steitz, B.; Brunner, H. |
Konferenzbeitrag Conference Paper |
| 2002 | Bioaktive Mikroarrays durch mikrostrukturierte Anlagerung von funktionellen Nanopartikeln Weber, A.; Knecht, S.; Schiestel, Thomas; Brunner, H.; Tovar, G.E.M. |
Konferenzbeitrag Conference Paper |
| 2001 | Extended X-ray absorption fine structure analysis of the bipyridine copper complexes in atom transfer radical polymerization Kickelbick, G.; Reinöhl, U.; Ertel, T.S.; Weber, A.; Bertagnolli, H.; Matyjaszewski, K. |
Zeitschriftenaufsatz Journal Article |
| 2001 | Structural investigations of oligomeric axially bridged ruthenium phthalocyanines by EXAFS spectroscopy Weber, A.; Ertel, T.S.; Reinöhl, U.; Bertagnolli, H.; Leuze, M.; Hanack, M. |
Zeitschriftenaufsatz Journal Article |
| 2000 | Structural investigations of tetra- and octasubstituted (phthalocyanine)ruthenium complexes by EXAFS spectroscopy Weber, A.; Ertel, T.S.; Reinöhl, U.; Bertagnolli, H.; Leuze, M.; Hees, M.; Hanack, M. |
Zeitschriftenaufsatz Journal Article |
| 2000 | Supported organometallic complexes. Part XX. Hydroformylation of olefins with rhodium(I) hybrid catalysts Lindner, E.; Auer, F.; Baumann, A.; Wegner, P.; Mayer, H.A.; Bertagnolli, H.; Reinöhl, U.; Ertel, T.S.; Weber, A. |
Zeitschriftenaufsatz Journal Article |
| 2000 | Synthesis, characterisation and catalytic application of sol-gel processed cationic palladium(II) complexes Lindner, E.; Baumann, A.; Wegner, P.; Mayer, H.A.; Reinöhl, U.; Weber, A.; Ertel, T.S.; Bertagnolli, H. |
Zeitschriftenaufsatz Journal Article |
| 1999 | Vorrichtung zur Messung der Oberflaechenspannung von Fluessigkeiten Janocha, B.; Renzow, D.; Mueller, Michaela |
Patent |
| 1990 | NADH-dependent mannitol dehydrogenase. Screening, isolation, kinetic parameters and behaviour in an enzyme membrane reactor Schmidt, K.; Stolz, P.; Lutz, S.; Weber, A.; Wiesner, W. |
Konferenzbeitrag Conference Paper |
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